Nur77 deficiency leads to systemic inflammation in elderly mice

nuri77The expression of nur77 gene and Nur77 are induced at 0–4 hr after 10 µM forskolin treatment in PC12 cells. (A) PC12 cells were treated with 10 μM forskolin.nur77Nur77 (also known as TR3 and NGFI-B) is nuclear receptor subfamily 4 group A member 1 (NR4A1) 1, 2, 3, 4.In general, it acts as a transcription factor localized in the nucleus